采用T1mapping序列定量评价肝脏局



彭洋现在哪里就诊 https://m-mip.39.net/fk/mip_9222434.html

ABSTRACT

Objectives:ToinvestigatethedifferenceofT1relaxationtimeonGd-EOB-DTPA-enhancedMRIinhepatocellularcarcinoma(HCC),hepaticfocalnodularhyperplasia(FNH)andcavernoushemangiomaofliver(CHL),andtoquantitativelyevaluatetheuptakeofGd-EOB-DTPAinthesethreefocalliverlesions(FLLs).

目的:探讨肝细胞癌(HCC)、肝局灶性结节增生(FNH)和肝海绵状血管瘤(CHL)在普美显增强磁共振成像上T1弛豫时间的差异，并定量评价Gd-EOB-DTPA在这三种肝脏局灶性病变中的摄取。

Results:TheT1PofCHLwassignificantlyhigherthanthoseofHCCandFNH(P0.05).ReductionofT1relaxationtimeonhepatobiliaryphasecouldbeobservedinallthreetypesoflesions.ThereweresignificantdifferencesofT1P,T1E,T1DandT1D%betweenFNH,CHLandHCC(P0.).SpearmancorrelationanalysisrevealedthatT1D%wasthebestindicatorfordiagnosticdifferentiation,withacorrelationcoefficientof0..Discriminantanalysisusingthreevariables(T1P,T1E,andT1D%)showedthattheclassificationaccuracywas88.2%.

结果:CHL的T1P显著高于HCC和FNH(P0.05)。肝胆相T1弛豫时间的缩短在三种类型的病变中都可以观察到。FNH、CHL和HCC之间T1P、T1E、T1D和T1D%差异显著(P0.)。Spearman相关分析显示T1D%是诊断鉴别的最佳指标，相关系数为0.。使用三个变量(T1P、T1E和T1D%)的判别分析表明，分类准确率为88.2%。

MaterialsandMethods:74patientsdiagnosedwithfocalliverlesionsunderwentGd-EOB-DTPA-enhancedMRIincludingT1mappingwereenrolled,consistingof51HCCs,10FNHs,and13CHLs.T1relaxationtimesoftheselesionsweremeasuredonpre-contrast(T1P)andonhepatobiliaryphaseimagesat20minuteaftercontrast(T1E).ThereductionofT1relaxationtimeonhepatobiliary(T1D)andthepercentagereduction(T1D%)wascalculated.ThedifferencesofT1P,T1E,T1DandT1D%intheseFLLswereanalyzed.TheusefulnessoftheseparametersforclassificationofFLLswasevaluated.

材料和方法:纳入74例经Gd-EOB-DTPA增强磁共振成像诊断为肝脏局灶性病变的患者，包括51例HCC、10例FNH和13例CHL。在增强前(T1P)和增强后20分钟(T1E)的图像上测量这些病变的T1弛豫时间。计算肝胆期T1弛豫时间的减少值(T1D)和百分比减少率(T1D%)。分析T1P、T1E、T1D和T1D%在这些肝脏局灶性病变中的差异。评估这些参数对肝脏局灶性病变分类的价值。

Conclusions:UptakeofGd-EOB-DTPAisdifferentbetweeninHCC,FNHandCHL.ThesethreelesionscanbedistinguishedusingT1mapping.

结论:HCC、FNH和CHL对Gd-EOB-DTPA的吸收是不同的。这三个病变可以采用T1mapping序列进行区分。

INTRODUCTION

Hepatocellularcarcinoma(HCC),focalnodularhyperplasia(FNH)andcavernoushemangiomaofliver(CHL)arethreefocalliverlesions(FLLs)


转载请注明：http://www.kmyoc.com/xglhl/12609.html